Tamoxifen For Men: Male Breast Cancer, Infertility and Gynaecomastia

What is Tamoxifen? Vaguely, Tamoxifen can be referred to as an anti-estrogen compound, but this is just on the surface, below the surface, you’ll discover that Tamoxifen could serve a variety of purposes, it is prescribed to both men and women depending on the doctor’s diagnosis of the symptoms experienced by either a male or female patient. Tamoxifen is a prescription medication that is used for the prevention of breast cancer in women, and breast cancer treatment in men and women, it has also been used in treating the McCune-Albright Syndrome. As mentioned earlier, it serves various purposes; it is an SERM, term for Selective Estrogen-Receptor Modulator that functions by decreasing factors that determine the increase in breast cells growth and at the same time, increasing factors that are detrimental to breast cells growth. The drug was developed in the late 1950’s but its efficacy as a medication for cancer and other conditions was not established until the 1970s/80s, since then, there have been a number of studies to determine its safety and efficacy in treating other conditions including low sperm count in men. Brand Tamoxifen includes Nolvadex, Genox and Soltamox, generic versions are also available.

Nolvadex-D – 20mg Tamoxifen Tablets

Tamoxifen for Male Breast Cancer

It could be said that men are at a lesser risk of having breast cancer because they do not have breasts, men do have breasts although not in the same fashion as a woman except in very rare cases; men have a small amount of breast tissue situated around the small area just beneath the nipples. The occurrence of breast cancer in men is low but it does occur, usually in older men. In treating breast cancer in men, especially in early stages, hormonal medication like Tamoxifen is often prescribed because it has a negative effect on the production of estrogen which is considered responsible for growth of breast tissues in men. Men with breast cancer are known to respond better to hormonal therapy in comparison to women, this is because cancerous breast cells in men can rely heavily on estrogen and progesterone hormones to grow; men produce both hormones in little quantities and Tamoxifen is effective in keeping cancerous breast cells isolated from the estrogen, this ensures that they do not grow and in some cases, cancerous cells begin to die.

Tamoxifen and Sperm Count: Male Infertility

A couple might be diagnosed with infertility if they find it difficult to conceive over a period of one year, either spouse could be infertile. If after testing the couple, results show that the reproductive problem lies in the man, it is termed ‘male infertility’ and ‘female infertility’ in the case of a woman. Infertility is a problem in some marriages today and either spouse should be ready to assist the other in overcoming this problem. Male infertility is the term used to describe the inability of a male to cause his fertile female partner to become pregnant. Generally, male fertility is dependent on the quality and quantity of a man’s sperm, reproduction becomes difficult and sometimes impossible when a man ejaculates a less-than-required amount of sperm or that of poor quality. About 7% of all men experience male infertility, which in most cases are related semen transport issues or semen deficiencies, which can be termed ‘oligospermia’.

Where does Tamoxifen come in? Combating male infertility using medications is only successful under certain conditions. Medical treatments for male infertility prove successful in cases where the cause of the problem is clearly defined i.e. knowing if the basis of the problem is hormonal, infectious, lifestyle-based, male reproductive tract abnormalities, etc. Medical therapy for male infertility is usually aimed at anti-inflammation, hormone-regulating medication, boosting sperm count and promoting erections and ejaculation. Tamoxifen for men comes in when male infertility has been determined to be related to hormonal issues. Tamoxifen citrate compound is an orally administered anti-estrogen medication that has been used in the treatment of male infertility. Tamoxifen works in stimulating sperm production by causing a rise in the release of gonadotropins. In current medical studies, Tamoxifen is administered to patients in an oral dose of 20 mg daily. As with other related drugs, there is a favourable response to Tamoxifen in some men, portrayed by an improvement in quality of their semen and increased rates of conception. Chances of conception are increased by up to 90% in up to one-third of couples, when the male partner has undergone Tamoxifen therapy. A combination therapy of Tamoxifen and Clomiphene can also be used.

                                 Tamoxifen 20mg Tablets

Tamoxifen 20mg Tablets

Tamoxifen for Male Gynaecomastia

Gynecomastia is a condition known to affect teen boys (pubertal gynecomastia) and male adults as well in which the breast tissues (meant to be present only in a small amount) become abnormally enlarged in boys or men, this sometimes causes nipple tenderness, discomfort or pain in the breast region. Gynecomastia usually occurs because of a hormonal imbalance, it occurs during infancy, adolescence, or mid to late life. It is important to distinguish Gynecomastia from breast enlargement that may occur due to large fat deposits as seen in obese men. Normally, the condition is expected to go away on its own after some time, but treatment options are available for cases that become severe or persistent. If cases of gynecomastia become severe in boys and cause substantial tenderness or embarrassment, a short course of Tamoxifen or Raloxifene medication may be recommended as these drugs are anti-estrogens, they can help to somewhat reduce the size of the breasts. When gynecomastia is the consequence of an underlying health problem, treatment of that problem improves the gynecomastia.

Conclusion

Cancer cases are a great reason for concern for doctors, patients and the medical field in general; Tamoxifen has shown an efficacy in the treatment of breast cancer in both men and women. Tamoxifen is also known to be a useful medication in cases of McCune-Albright syndrome, persistent or severe gynecomastia and prostate cancer although its use in the treatment of some of these cases has not been approved by the US FDA. Not being approved by the FDA does not keep your doctor from prescribing a drug to you especially in cases where he feels the drug’s benefits definitely outweigh any risks of taking it, consult your doctor before using Tamoxifen in any case. Check out our list of top recommended online pharmacies for the best deals on Tamoxifen purchase.