Tamoxifen Adverse Effects: Do They Outweigh Its Benefits?

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Tamoxifen is an orally administered drug compound used in the prevention and treatment of breast cancer in both women and men. Depending on symptoms experienced by patients and the doctor’s prescription, Tamoxifen may also serve for the treatment of certain other medical conditions though it’s used in the treatment of such conditions have not been approved by the FDA. Though Tamoxifen was developed in the late 1950’s, its efficacy in the treatment of breast cancer and a few other medical conditions was not established until the 1970s/80s, a number of studies have been conducted since then to determine its safety and efficacy in treating other medical conditions including low sperm count in men and Albright Syndrome. Brand Tamoxifen includes Nolvadex, Genox and Soltamox, generic versions are also available. Tamoxifen has been tested in different series of studies: in cases of delayed puberty in boys, tamoxifen therapy seemed to trigger the pituitary-gonadal axis to produce hormones that initiate pubertal development; in another study to test the hormonal effects of Tamoxifen in Oligospermic men, patients were orally administered 20mg of Tamoxifen for about six to nine months, during evaluation, results showed that a notable increase in gonadotropin, testosterone, and estradiol levels had occurred, leading to a notable increase in sperm density in men with oligospermia defined as ‘below 20 X 10(6)/ml’; results of other studies can be found on the web.

Tamoxifen Side Effects Hair Loss

Every drug comes with side effects and Tamoxifen is not an exception, even over-the-counter drugs like those for common cold could make you drowsy, knowing what you should expect in terms of side effects of drugs helps you to handle such side effects well. Side effects of drugs can range from mild to severe but severe side effects rarely occur, at least this is what makes the drugs usable. What are the most common side effects of Tamoxifen? This is a question that many Tamoxifen users ask, the first person to seek such information from is your doctor or pharmacist, and you can also use the information leaflet (you can find drug interactions and contraindications here) that comes with a pack of the drug. The kind of side effects encountered with the use of Tamoxifen might differ per individual or between sexes i.e. male or female. The most common side effects encountered in the use of Tamoxifen include hot flashes, headaches, dizziness, nausea, constipation or indigestion, troubled breathing when at rest, feeling of warmth, fatigue, dry skin, hair thinning, leg cramps and muscle or bone pain; patients often experience these side effects in mild degrees and as the body adjusts to the therapy, certain side effects start to wear away, but if they do become discomfiting, see your doctor as soon as possible. possible.

Long-Term Side Effects of Tamoxifen

Long-term side effects define those side effects that remain even after treatment the preconceived treatment period; sometimes these side effects extend beyond months or sometimes even years after treatment. Your doctor would only prescribe you Tamoxifen in the event that he sees its benefits as outweighing any risks that can come about as a result of your treatment plan, but if you have had previous treatment for any medical condition that resulted in long-term side effects, you might be advised by your doctor to carry out physical examinations like scans or body-fluid tests. Side effects of hormonal treatments like Tamoxifen tend to subside at the end of the treatment period but few individual patients might experience long-term side effects, they are not different from the usual side effects which include headaches, hot flashes, irregular sweating experiences, loss of libido, dizziness, nausea, increase or decrease in weight, constipation, dry skin and rashes and a few others. Oftentimes in less complicated cases, Tamoxifen is prescribed to out-patients by doctors, who continue to monitor a patient’s progress with the therapy in case there is a need to discontinue the treatment or make any adjustments.

Tamoxifen Weight Gain

Tamoxifen Weight Gain

Gaining body-mass during Tamoxifen treatment seems to be something with a 50-50 chance of occurrence as some people also lose weight during Tamoxifen treatment. A medical study carried out in 1997 ended with results showing that there is no significant correlation between Tamoxifen use and weight gain as the normal population also gained weight at about the same proportion as those using Tamoxifen, perhaps weight gain as such is a function of eating healthy and general wellbeing. The study states in quotes “These findings may help to alleviate some concerns of both physicians and patients when tamoxifen is the drug of choice for adjuvant therapy”.


Tamoxifen is a prescription medication approved by the FDA for the treatment of a kind (one that relies on estrogen for growth) of breast cancer in men and women, research is still being conducted to ascertain and improve the effects of Tamoxifen in the treatment of breast cancer. In the case of cancer, Tamoxifen therapy might last for up to five years but depending on the situation, the length of time of treatment can be adjusted. Tamoxifen is also prescribed off-label for male infertility and a few other medical conditions in which a healthcare provider may consider it a viable treatment option. After going through the benefits and risks posed by Tamoxifen therapy, your doctor will either prescribe the drug to you or advise you to embrace some other more predictable option. We have a list of online pharmacies that offer great deals where you can buy Tamoxifen 20mg or any other strength at affordable prices.

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